Thursday, May 30, 2013

Quora Grew More Than 3X Across All Metrics In The Past Year

Image (1) quora-picture.png for post 260879Quora famously doesn't share its growth numbers. Due to this furtiveness, many people speculate that it is not growing. On Quora even:?Has Quora as a business failed??is a Quora question that smacked me in the face right as I opened the site to research this article.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/TWGT5FifNO8/

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Wednesday, May 29, 2013

A Flood-Powered Gate That Automatically Raises As the Waters Rise

Deploying the improved infrastructure that will hopefully help prevent future tsunamis from devastating Japan is an expensive endeavour. So researchers across the country are developing new and cheaper ways to protect Japan, like this innovative floodgate that deploys automatically when waters come rushing in?no power or human operators required.

And instead of using water-powered turbines or other complicated mechanisms that require constant maintenance, the floodgate simply uses a reservoir underneath and a highly buoyant material. As the flood waters rise, the reservoir fills, and the gate floats upwards, sealing off an area up to 33 feet across and as high as 16 feet. So while a tsunami can still rush inland, buildings and other structures can be protected even when electricity's been knocked out.

A Flood-Powered Gate That Automatically Raises As the Waters Rise

[Asahi via Damn Geeky]

Source: http://gizmodo.com/a-flood-powered-gate-that-automatically-raises-as-the-w-510091624

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Sheryl Sandberg, COO of Facebook, live at D11

Sheryl Sandberg, COO of Facebook, live at D11

Sheryl Sandberg has served as the chief operating officer of the world's most popular social network since 2008, and today she's taking the stage at D11 here in Rancho Palos Verdes, California. She's kicking off a day of high-profile interviews just hours after Apple CEO Tim Cook got things started last night, and we're expecting her to be grilled on all manners of things -- the company's stock price, the future of mobile advertising, the success (or failure) of Facebook Home, international growth and how many Likes this here liveblog will receive. Join us after the break for the blow-by-blow, won't you?

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/hOWxx8Ch7Vw/

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U.S. shuts digital money system it suspects of criminal links

By Emily Flitter

NEW YORK (Reuters) - U.S. authorities revealed on Tuesday they have shut down a Costa Rica-based money transfer company they said helped cyber criminals around the world launder around $6 billion in illicit funds using digital currency.

In a statement, officials said authorities in Spain, Costa Rica and New York arrested five people on Friday and seized bank accounts and Internet domains associated with the company, Liberty Reserve.

Costa Rican prosecutor Jos? Pablo Gonz?lez said Liberty Reserve and related businesses were used to launder funds from child pornography websites and drug trafficking.

Digital currency is made up of transferable units that can be exchanged for cash. Over the past decade, its use has expanded, attracting attention from the media and Wall Street. The most widely known digital currency is called Bitcoin. Liberty Reserve's currency was not connected to Bitcoin.

Along with the five arrests, prosecutors filed charges against two more company employees, who were still at large in Costa Rica.

According to an indictment filed in U.S. District Court for the Southern District of New York, "Liberty Reserve has emerged as one of the principal means by which cyber-criminals around the world distribute, store and launder the proceeds of their illegal activity."

The indictment said the company had more than a million users worldwide, including at least 200,000 in the United States, and virtually all of its business was related to suspected criminal activity.

The company's founder, Arthur Budovsky, was arrested, along with his deputy, Azzedine El Amine; co-founder Vladimir Kats, and two technology designers, Maxim Chukarev and Mark Marmilev. The two still at large are Ahmed Yassine Abdelghani and Allan Esteban Hidalgo Jimenez, who at various times managed the company's day-to-day operations. According to the indictment, almost all of the men used the alias, Eric Paltz.

According to the indictment, Liberty Reserve's currency unit was called the "LR." The company's users opened accounts at Liberty Reserve giving only a name, address and date of birth that the company made no attempt to verify. Once a user had a Liberty Reserve account, he or she could use cash to purchase LRs from third-party exchange merchants, which traded LRs with each other in bulk and charged fees to make the exchanges between LRs and hard cash.

Liberty Reserve users could transfer the digital currency units called LRs to each other, to be redeemed in different parts of the world for cash using the third-party exchange companies. The indictment said Liberty Reserve did not collect any banking or transaction information from the third-party exchange companies. It also let its users hide their Liberty Exchange account numbers when making transactions, which offered another opportunity for the users to mask their true identities.

The company processed around 12 million financial transactions per year. Since it began operating in 2006, the indictment said, Liberty Reserve laundered around $6 billion in criminal proceeds.

On Tuesday, the company's website, www.libertyreserve.com, displayed the message: "This domain name has been seized by the United States Global Illicit Financial Team."

It was not clear whether the people arrested in Spain and Costa Rica would be extradited to the United States or when the two people arrested in Brooklyn, New York, would appear in court.

A spokeswoman for the U.S. Attorney for the Southern District of New York declined to comment.

Regulatory obligations to combat money laundering have emerged as a major challenge to digital currency firms. The U.S. Treasury Department's anti-money laundering unit, the Financial Crimes Enforcement Network (FinCEN), issued guidance in March that labeled digital currency firms as money transmitters, thereby obliging them to enact anti-money laundering programs and register with FinCEN.

A top Bitcoin exchange, Mt. Gox, failed to register with FinCEN earlier this month and had its U.S. dollar accounts seized by authorities.

Over the past week, a Bitcoin unit has traded at around $130.

(Reporting by Emily Flitter in New York Additional reporting by Brett Wolf in St. Louis and Isabella Cota Schwarz in Costa Rica; Editing by Jeffrey Benkoe, Tim Dobbyn and Jan Paschal)

Source: http://news.yahoo.com/u-shuts-alleged-cyber-criminal-money-transfer-system-144155238.html

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Zotac ZBOX ID89 Plus Intel Chipset Driver 9.3.0.1021 for Windows 7/Windows 8

Specifications:
?
Chipset
- Manufacturer Intel
- Chipset Name H61 Express
- GPU Intel HD Graphics 2500

CPU Compatibility
- Name Intel Core i5 3470T (dual-core, 2.9 GHz) (Up to 3.6 GHz, Turbo)
- Socket LGA1155
- Frontside Bus NA

Memory
- Memory Type DDR3
- Memory Speed 1600 MHz
- Slots 2 x 204-pin SO-DIMM
- Capacity 4GB (up to 16GB)

Expansions
- Expansion Slots na

3D API
- DirectX 11
- OpenGL 4.2

Networking
- Ethernet 2 x 10/100/1000Mbps
- WiFi 802.11n/g/b + Bluetooth 4.0

Audio
- Analog Headphone jack Microphone jack
- Digital 8-ch via HDMI S/PDIF

Storage
- Hard Drive 500GB 5400RPM HDD
- Optical Drive na
- Memory Card Reader 4-in-1 (MMC/SD/SDHC/SDXC)

Ports
- DVI (single-link)
- HDMI 1 (HDCP w/8-channel digital audio)
- DisplayPort
- SATA 1 (SATA 3.0 Gb/s)
- eSATA na
- IDE na
- PS2 na
- Serial Port na
- USB Ports 2 USB 3.0 (1 on top, 1 front) 2 USB 2.0 (2 on back panel)
- Firewire

Cooler
- Smartfan

Form Factor
- mini-PC

General SLI
- Not Supported

Maximum Resolution
- na

Other Graphics Output
- 1 DVI / 1 HDMI

It is highly recommended to always use the most recent driver version available.

Do not forget to check with our site as often as possible in order to stay updated on the latest drivers, software and games.

Try to set a system restore point before installing a device driver. This will help if you installed a wrong driver. Problems can arise when your hardware device is too old or not supported any longer.

Source: http://drivers.softpedia.com/get/MOTHERBOARD/Intel/Zotac-ZBOX-ID89-Plus-Intel-Chipset-Driver-9301021-for-Windows-7-Windows-8.shtml

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After smoothing tensions in Slovenia, PM Bratusek seeks to win over Europe

If a week is a long time in politics, then two months can feel like an eternity. That has certainly been the case for Slovenian Prime Minister Alenka Bratusek.

Ms. Bratusek, the country's first female premier and the telegenic leader of Pozitivna Slovenija (Positive Slovenia), only took office in late March. But she has spent the short weeks since attempting to negotiate passage between the Scylla of a European Commission that demands solutions for Slovenia?s ailing banks and the Charybdis of a public with limited stomach for further austerity.

And while Brussels' verdict on Slovenia?s proposed reforms is expected tomorrow, she has already won plaudits at home for her handling of Slovenia?s biggest crisis since its secession from Yugoslavia in 1992.

RECOMMENDED: Think you know Europe? Take our geography quiz.

"So, so far, so good," a leading Slovenian economist says of the new premier?s performance. The economist, who is close to the government, was not authorized to speak and so asked not to be named. "[She] has a nice public appearance ,and she hasn't antagonized the public in the way the former premier always did. Working in her favor is also the fact that she is a completely new figure in our politics," the economist told The Christian Science Monitor.

FINANCIAL CRISIS

The immediate cause of Slovenia?s current travails is a familiar problem across the eurozone?s struggling periphery: undercapitalized and struggling banks. Slovenia, a nation of 2 million tucked in between Austria, Italy, Croatia, and Hungary, has been in recession since 2011.

After independence ? and particularly after membership of the European Union in 2004 and the euro in 2007 ? Slovenian banks extended generous credit lines to the "managers" of many formerly state-run companies to purchase controlling stakes in these businesses. These so-called "management buyouts" were politically popular, as they ensured that Slovenian industry remained in national hands.

But questions have been raised about the probity of these management buyouts. In the wake of the 2008 financial crisis and the tightening of credit globally, many of the loans made to fund these purchases are underwater, taking Slovenia?s once-formidable banking sector with them.

Further, the bursting of a construction bubble that grew from 2004 to 2008 has left empty properties across the country, particularly in Ljubljana, and tens of thousands of unemployed. Anecdotally, emigration has increased.

CORRUPTION

On the streets of Slovenia, frustration with the economy has been compounded by the corruption that has dogged Slovenian politics in recent years.

Bratusek only became leader of Positive Slovenia when former President Zoran Jankovic was forced to resign earlier this year. A state anti-corruption commission found that he failed to report fully ?2.4 million ($3.1 million) of assets accrued during his six years in office. (He remains mayor of the capital, Ljubljana.)

The same anti-corruption commission also found then-Prime Minister Janez Jan?a guilty of systematically violating law on the reporting of assets. A coalition headed by Mr. Jan?a?s center-right Slovenian Democratic Party fell in February, to be replaced by a new coalition with Bratusek and Positive Slovenia at its apex.

Jan?a?s downfall was also fueled in part by protests that began last November in Maribor, the country?s second-largest city. Tens of thousands protested against Mayor Franc Kangler, also accused of corruption. Here, for the first time since independence, Slovenian riot police used tear gas on protesters.

Mayor Kangler was forced to step down in December, but not before the protests had spread across Slovenia.

STAVING OFF A BAILOUT

The fallout from the corruption probe left the relatively unknown Bratusek as an unexpected beneficiary. But while Bratusek might be a new face on Slovenian television screens, she has a relatively long political pedigree.

Although only elected to the Slovenian parliament in 2011, for six years she was head of the directorate of the state budget at the ministry of finance under the former Liberal Democracy of Slovenia (LDS) administration that ruled from independence until 2004. That has helped her navigate the tricky political maneuvering currently required in Slovenia, where Europe and the public are pulling in opposite directions.

"If the politicians are too tough, they are out at home. If they are too soft, they are out from Brussels," says Primoz Cirman, a leading economics writer for the Slovenian newspaper daily Dnevnik. "Right now [the government] are trying find out where the equilibrium is."

Earlier this month, Bratusek announced a series of measures aimed at convincing the European Commission that Slovenia, the most developed economy in the former Yugoslavia, can plug a multibillion-euro hole in its banks? balance sheets and stave off a eurozone-led bailout.

Proposals include the creation of a "bad bank" to allow the banking sector to offload non-performing debts; a 2 percent increase in VAT; and the sales of 15 publicly-owned businesses including Telekom Slovenia and national carrier Adria Airways.

SMALLER PROTESTS

Bratusek's presence has softened the country's ongoing demonstrations, whose size and frequency have decreased in recent months.

In Metelkova, a former barracks of the Yugoslav National Army in Ljubljana that has been home to squatters since 1993, Anej Korsika from the nascent Initiative for Democratic Socialism explained that the change of government has taken some of the sting out of the protest movement.

"The struggle under Jan?a was much easier," he says. "[Jan?a] called the protesters ?Communist zombies? and ?leftist fascists? and all these things which really infuriated people and really mobilized them to go onto the streets in bigger numbers than they would otherwise."

RECOMMENDED: Think you know Europe? Take our geography quiz.

Related stories

Read this story at csmonitor.com

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Source: http://news.yahoo.com/smoothing-tensions-slovenia-pm-bratusek-seeks-win-over-220324175.html

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Monday, May 27, 2013

Receiving A Gold Plated iPad At Hotel Check-In Is Normal, Right?

Receiving A Gold Plated iPad At Hotel Check-In Is Normal, Right?

You know the drill. You pull up to a Super 8 Motel with the vacancy light on, you argue with the attendent about getting a room away from the ice machine, you whip out your AAA card for extra savings and then you take the 24-karat gold-plated iPad the attendant hands you and head off to your room to stockpile some free soap. Boom.

Read more...

    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/3MSW_8A6ygg/receiving-a-gold-plated-ipad-at-hotel-check-in-is-norma-509918301

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Blackhawks beat Red Wings 4-1 to stay alive

CHICAGO (AP) ? The power play returned in the second half of the second period. All it took was one brilliant tip by one of the youngest players on the ice and a well-placed shot by the captain of a team in trouble.

All that tinkering paid off when the Chicago Blackhawks needed it the most.

Jonathan Toews and Andrew Shaw each had a timely power-play goal, and the Blackhawks avoided elimination with a 4-1 victory over the Detroit Red Wings on Saturday night in Game 5 of the second-round playoff series.

"I've been saying it over and over the last couple of days: Stay positive and stick with it and things have to turn your away eventually, and they did tonight," Toews said.

The 21-year-old Shaw added his third career playoff goal in the third as the Blackhawks stopped the Red Wings' three-game winning streak by creating chaos in front of Jimmy Howard, who had shut down Chicago's attack while moving Detroit to the brink of the Western Conference finals.

With the sellout crowd chanting "Ho-ward! Ho-ward!" in an attempt to shake him, the standout goalie made 41 saves in another solid performance. But the Blackhawks created enough quality chances that he simply couldn't stop all of them.

"We knew it. We knew we were going to have to weather the storm early against them and I thought we did that," Howard said. "We got it going there, but they just kept coming and coming."

Bryan Bickell scored the first goal of the game and Corey Crawford had 25 stops for Chicago, which managed only two goals during its first three-game losing streak of the season.

Daniel Cleary scored for the second straight game for Detroit, which will have another chance to close out the top-seeded Blackhawks in Game 6 on Monday night. That will be at home, too, where the Red Wings are 4-1 in this postseason.

"We weren't good enough tonight as far as our plan we have to play to be successful," Red Wings coach Mike Babcock said. "There was too much space and they were just freewheeling around having fun. It just goes to show you how hard it is to win and you've got to compete and do things right in order to be successful."

Detroit trailed 1-0 before Cleary completed a strong rush during a 4-on-4 stretch in the second period, beating Crawford from a tough angle on the left side for his fourth goal of the postseason. Henrik Zetterberg set up the score by throwing the puck across the crease while Brendan Smith was streaking toward the net.

Back came Chicago, which responded with two of its best power plays in weeks. The Blackhawks had converted only three of their first 25 chances in the postseason, and coach Joel Quenneville tried all sorts of combinations in practice to no avail.

He finally got what he wanted in Game 5.

First, Shaw had a perfect tip on Duncan Keith's slap shot to make it 2-1 at 13:08. Then Justin Abdelkader received his second penalty, this one for cross checking, and Toews wristed a shot off Howard's facemask and into the upper right corner.

"Good things come from shooting the puck," Shaw said. "There's rebounds, there's loose pucks, and we had all guys converging to the net and we just kept picking them up and hemmed them in there and tired them out and we were rewarded."

It was Toews' first playoff goal since April 21, 2012, at Phoenix, snapping a scoreless postseason drought of 10 games. It also came after he appeared frustrated while committing three penalties in the second period of Game 4.

The captain was mobbed by his teammates after he skated to the boards, and the crowd of 22,014 roared its approval.

"It is a relief. It's a confidence builder," Toews said. "You know the way you're working is adding up to something. You want to keep that going now. If I keep shooting the puck there's a good chance it's going in. The goaltender has to make a stop."

Chicago got off to a good start with a 4-1 victory in Game 1 of the series, but it had been all Detroit since that opening win. The Red Wings turned up the pressure on defense and Howard had an amazing 86 stops on 88 shots over three straight wins that pushed the Blackhawks to the edge of an early postseason exit.

Back at home after managing just one goal in a pair of losses in Detroit, the Blackhawks came out with a spirited opening period. Brent Seabrook, who played only 12 minutes in Game 4, and Bickell each delivered a huge hit in the opening minutes.

Bickell then plowed ahead to set up Chicago's first goal since the third period of Game 3. Howard turned away Bickell's first charge, but he skated around to the other side of the net and was right there to slam home on the rebound when Patrick Kane was denied.

Bickell pumped both his arms after he gave the Blackhawks their first lead in a week. It was the fourth goal of the season for physical forward, but his first since Game 4 of the first-round series against Minnesota.

The Red Wings then rushed down the ice, and Crawford turned away quality opportunities for Joakim Andersson and Gustav Nyquist. Crawford made 11 saves in the opening period.

"It's hard to match that when their backs were against the wall," Cleary said. "But we have to be ready to go like our backs are against the wall on Monday."

NOTES: Chicago Blackhawks Charities donated their portion of the Split the Pot money from Game 5 to the OK Strong Disaster Relief Fund to benefit the victims of the deadly tornadoes in Oklahoma.

___

Jay Cohen can be reached at http://www.twitter.com/jcohenap

Source: http://news.yahoo.com/blackhawks-beat-red-wings-4-1-stay-alive-025952423.html

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Climate researchers discover new rhythm for El Ni?o

May 27, 2013 ? El Ni?o wreaks havoc across the globe, shifting weather patterns that spawn droughts in some regions and floods in others. The impacts of this tropical Pacific climate phenomenon are well known and documented.

A mystery, however, has remained despite decades of research: Why does El Ni?o always peak around Christmas and end quickly by February to April?

Now there is an answer: An unusual wind pattern that straddles the equatorial Pacific during strong El Ni?o events and swings back and forth with a period of 15 months explains El Ni?o's close ties to the annual cycle. This finding is reported in the May 26, 2013, online issue of Nature Geoscience by scientists from the University of Hawai'i at Manoa Meteorology Department and International Pacific Research Center.

"This atmospheric pattern peaks in February and triggers some of the well-known El Ni?o impacts, such as droughts in the Philippines and across Micronesia and heavy rainfall over French Polynesia," says lead author Malte Stuecker.

When anomalous trade winds shift south they can terminate an El Ni?o by generating eastward propagating equatorial Kelvin waves that eventually resume upwelling of cold water in the eastern equatorial Pacific. This wind shift is part of the larger, unusual atmospheric pattern accompanying El Ni?o events, in which a high-pressure system hovers over the Philippines and the major rain band of the South Pacific rapidly shifts equatorward.

With the help of numerical atmospheric models, the scientists discovered that this unusual pattern originates from an interaction between El Ni?o and the seasonal evolution of temperatures in the western tropical Pacific warm pool.

"Not all El Ni?o events are accompanied by this unusual wind pattern" notes Malte Stuecker, "but once El Ni?o conditions reach a certain threshold amplitude during the right time of the year, it is like a jack-in-the-box whose lid pops open."

A study of the evolution of the anomalous wind pattern in the model reveals a rhythm of about 15 months accompanying strong El Ni?o events, which is considerably faster than the three- to five-year timetable for El Ni?o events, but slower than the annual cycle.

"This type of variability is known in physics as a combination tone," says Fei-Fei Jin, professor of Meteorology and co-author of the study. Combination tones have been known for more than three centuries. They where discovered by violin builder Tartini, who realized that our ear can create a third tone, even though only two tones are played on a violin.

"The unusual wind pattern straddling the equator during an El Ni?o is such a combination tone between El Ni?o events and the seasonal march of the sun across the equator" says co-author Axel Timmermann, climate scientist at the International Pacific Research Center and professor at the Department of Oceanography, University of Hawai'i. He adds, "It turns out that many climate models have difficulties creating the correct combination tone, which is likely to impact their ability to simulate and predict El Ni?o events and their global impacts."

The scientists are convinced that a better representation of the 15-month tropical Pacific wind pattern in climate models will improve El Ni?o forecasts. Moreover, they say the latest climate model projections suggest that El Ni?o events will be accompanied more often by this combination tone wind pattern, which will also change the characteristics of future El Ni?o rainfall patterns.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/8uaxbC6Z_5Y/130527100628.htm

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Sunday, May 26, 2013

Get Super Fit At Any Age

Nobody ages backward. Now that we have that unpleasant fact out of the way, let's get to some good news: You don't need to be a genetically blessed model or have a plastic surgeon on speed dial to keep your body in remarkable shape. Instead, just dive into the closest thing we have to a fountain of youth: fitness.

With the right workout strategy, one targeted for your age and physiology, you can fight back against the inevitable slowdown, build muscle and keep your weight in a happy place. Whether you're blowing out the candles on your 30th-birthday cake or planning a big 5-0 bash, follow our decade-by-decade game plan?based on advice from scientists, nutritionists and fitness pros?to get the body you want right now.

Get Super Fit At Any Age

What's Happening

You are still close to peak potential for being in incredible shape (see soccer goalie and Dancing with the Stars alum Hope Solo and tennis star Serena Williams). But your body is in the early stages of rebellion. "Starting in their 30s and early 40s, women lose about 5 pounds of muscle in every decade," says Wayne Westcott, PhD, instructor of exercise science at Quincy College in Massachusetts.

That's a body bummer, since the more muscle tone you have, the leaner you look (because muscle is more compact than fat) and the more calories you burn at rest (because it takes more energy to maintain muscle than fat). In fact, according to data from the National Health and Nutrition Examination Survey, a normal-weight woman is likely to gain 5 percent of her body weight per decade between the ages of 25 and 45. Even so, says Westcott, if you're active, "you're still in control."

7 Easy Ways to Kick-Start Your Metabolism

Fitness Game Plan

It's essential to stay at your ideal weight during this decade to set yourself up for success later, when biology makes it more challenging. That means cardio is key. A 2010 Harvard study found that premenopausal women in their 30s who rode a bike for more than four hours a week, for instance, were 26 percent less likely to gain more than 5 percent of their starting body weight over the course of 16 years.

You can also get good results from 30 to 40 minutes of running, a dance class or whatever other heart-pumping exercise you like four or five times a week, says Wendy Kohrt, PhD, professor of medicine at the University of Colorado's division of geriatric medicine. Mix in muscle-building exercises to jack up your metabolism even further and tone up: Do as many reps as you can of a strength move (say, push-ups or lunges) for one minute. Follow that up with two minutes on a bike at a challenging pace. Continue alternating, varying the strength move each time, for 15 minutes.

10 Minutes to All-Over Toned

Test Yourself

To check your cardiovascular fitness, stand facing a 12-inch-high bench or box. Step up on and off the box for three minutes. Then count your pulse for a minute. It should be between 58 (excellent) and 110 (average). If you retake the test in your 40s, your pulse should be between 60 and 112 (in your 50s, between 63 and 118).

Nutrition Game Plan

To lose weight at this age, a moderately active 5-foot-5, 150-pound woman should consume around 1,500 calories a day (but no fewer!), says Jackie Newgent, RD, author of 1,000 Low-Calorie Recipes. That can lead to a loss of 5 pounds in about 5 weeks, 10 pounds in about 10 weeks and 15 pounds in about 15 weeks. The secret to regulating your hunger hormones and making chip binges less likely, according to Health Contributing Nutrition Editor Cynthia Sass, RD, is eating on a regular schedule. That means having breakfast within an hour of waking up and spacing remaining meals three to five hours apart. And make sure you're getting 1,000 milligrams of calcium a day: The mineral is needed to help muscles contract and maintain strong bones. "By the middle of this decade, what you have in your 'bone bank' is what you have for life, but you can build and maintain it," Sass says. Good calcium sources include yogurt, canned salmon (which typically packs more than fresh), almonds and leafy greens such as kale.

The 20 Best Foods to Eat for Breakfast

Get Super Fit At Any Age

What's Happening

Thanks in part to hormonal fluctuations, your metabolism starts to sputter as you head into menopause, causing weight gain. If you skip out on strength training, you'll likely lose another 5 percent of your muscle mass, Westcott says. But (deep breath!) these are just "ifs" and general rules. In fact, the average age of female participants in the Ironman World Championship is 41.

Fitness Game Plan

While you need to continue with your cardio, strength training?any exercise that puts progressively greater force on your muscle and bone?is more important than ever for keeping muscle mass and bone density at their peak, and fending off unwanted pounds. Think gradually working up to heavier dumbbells or adding more reps of push-ups. "The key to a better metabolism is breakdown and repair of muscles," Westcott says.

Test Yourself

To check your overall body strength, get in the plank position. You should be able to hold it for at least 60 seconds. If you're in your 30s, raise the benchmark to 70 seconds. If you're in your 50s, lower it to 50 seconds. Retest yourself every four weeks after starting a strength program to see how your results improve.

Nutrition Game Plan

Don't cut your calories any further. But do aim for balance in your meals, advises Sass, by focusing on foods rich in good carbohydrates (like fruit and whole grains), lean protein (fish, yogurt and beans) and healthy fat (avocado, nuts and olive oil). The carbs will give you the fuel you need to stay energized all day, while the protein and fat will help you heal and maintain the muscle that's so crucial to maximizing your metabolism in your 40s, Sass adds.

Superfood Secrets for a Long and Healthy Life

Get Super Fit At Any Age

What's Happening

As you go through menopause, your estrogen production declines, accelerating bone loss. This is why you can expect up to a 30 percent decline in bone mass in your 50s if you skip exercise?setting you up for osteoporosis. Lack of estrogen has also been linked to weight gain, especially around the abdomen. Then again, there are ways to maintain your fit body?just ask marathoner Joan Benoit Samuelson, 56.

Fitness Game Plan

Turn to a combination of regular walking, strength training and stretching to keep yourself lean and strong?and safe, since in the next couple of decades, balance issues can lead to injuries. "Stretching not only has an effect on flexibility but also builds muscle strength," Westcott says. Yoga's a great addition to your routine if you're not already into it: According to a study at the Fred Hutchinson Cancer Research Center, subjects between the ages of 45 and 55 who did yoga at least once a week for four or more years gained about 3 fewer pounds than folks who didn't hit the mat.

Best Yoga Poses for Your Trouble Spots

Test Yourself

Stand with feet together, hands on hips. Place bottom of right foot on inner left calf, just below knee. Hold for as long as possible. Repeat on opposite side, then calculate your average hold time. If you can maintain the position for more than 50 seconds on average, you have excellent balance (woo-hoo!). If you crumble after 25 seconds or less, improve your time by incorporating yoga or tai chi into your weekly workout routine.

Nutrition Game Plan

You should keep aiming for that 1,500-a-day calorie count, and make sure you're eating enough protein. By the time you reach 50, you don't process it as well as you did in previous decades, Westcott says, so you have to exceed the recommended daily amount of 46 grams.

Here's more motivation to get it now: A study at the University of Texas Medical Branch at Galveston found that eating 4 ounces of protein-rich food per meal (as opposed to eating 12 ounces all in one sitting) maximizes your body's muscle-building rate by up to 50 percent. Westcott recommends following up a sweat session with foods like chicken breast or chocolate milk. Turns out, a glass of red wine could help your anti-aging efforts, too. A recent study in the journal Menopause suggests that having one or two glasses a day may help slow bone breakdown. Cheers to that!

This article originally appeared on Health.com.

***

More from Health.com:

24 Fat-Burning Ab Exercises

Best Yoga Poses for Your Trouble Spots

How to Fix the 9 Worst Signs of Aging

Source: http://abcnews.go.com/Health/Wellness/super-fit-age/story?id=19249678

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Vintage Apple computer auctioned off for $668,000

(AP) ? An auctioneer says one of Apple's first computers ? a functioning 1976 model ? has been sold for a record 516,000 euros ($668,000).

German auction house Breker said Saturday an Asian client, who asked not to be named, bought the so-called Apple 1, which the tech company's founders Steve Jobs and Steve Wozniak built in a family garage.

Breker claims it is one of only six known remaining functioning models in the world. Breker already sold one last year for 492,000 euros.

It says the computer bears Wozniak's signature. An old business transaction letter from the late Jobs also was included.

The Apple 1, which was sold for $666 in 1976, consisted of only the circuit board. A case, a keyboard and a screen had to be bought separately.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-05-25-Germany-Apple%20Auction/id-6503fcb9f35a4835bf4cb3bb8989f2f7

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Syrian opposition struggles for unity as battle rages

By Khaled Yacoub Oweis

ISTANBUL (Reuters) - Syria's opposition resumed talks on Saturday aimed at closing their fractious ranks, as government forces launched a fierce onslaught on a rebel-held border town to try to gain the upper hand in the civil war.

A failure of the opposition to unite could weaken the hand of Russia and the United States, co-sponsors of a proposed peace conference on the war, which has killed 80,000 and threatens to spill over borders and whip up wider sectarian violence.

The U.S. and Russian foreign ministers are to meet in Paris on Monday to discuss how to shepherd Syrian President Bashar al-Assad and the opposition into the talks in Geneva.

As opposition leaders met in Istanbul, Assad's forces reinforced by Iranian-backed Shi'ite Lebanese Hezbollah fighters unleashed heavy artillery and tank fire to try to seize more rebel terrain in the Sunni Muslim border town of Qusair on Saturday, sources on both sides said.

Syria is becoming a proxy conflict between Shi'ite Iran which backs Assad, whose Alawite faith is an offshoot of Shi'ism, and Arab states such as Saudi Arabia and Qatar which support Assad's mostly Sunni enemies.

George Sabra, the acting head of the opposition Syrian National Coalition, said thousands of fighters from Iran and Hezbollah were involved in the attack on Qusair, close to the Lebanese border, and in battles in the capital Damascus.

Hezbollah leader Hassan Nasrallah said his group would stay in the Syrian conflict "to the end of the road" and would win the war for Assad's government.

"We accept this responsibility and will accept all sacrifices and expected consequences of this position," he said in a televised speech, speaking from an undisclosed location. "We will be the ones who bring it victory, God willing."

Assad's forces are believed to have seized about two-thirds of Qusair and largely surrounded the rebels. But the price was high and rebels insisted they were preventing further advances.

The insurgents see Qusair as a critical battle to preserve cross-border supply lines and deny Assad a victory they fear may give him the edge in the prospective peace talks next month.

More than 22 people in opposition-held areas were killed by Saturday afternoon, most of them rebels, and dozens wounded, according to pro-opposition monitoring group the Syrian Observatory for Human Rights.

The pro-opposition Syrian Network for Human Rights said 73 people were killed by Assad's forces, and opposition campaigner Adib Shishakly said Nasrallah lost 75 fighters in the battle for Qusair and that rebel defenders were doing "an excellent job."

U.S. CONCERNS

The United States, concerned by the rising influence of hardline Islamists, has pressed the Syrian National Coalition to resolve its divisions and bring more liberals into the fold.

Sources at the coalition, which began its third day of meetings, said major players would focus on such international demands for a broadening of the Islamist-dominated group, leaving leadership issues for later.

Attempts to strike a grand bargain involving veteran liberal campaigner Michel Kilo and businessman Mustafa al-Sabbagh, Qatar's point man in the coalition, went nowhere in talks that stretched overnight, senior coalition sources said.

"We are back to square one," one of them told Reuters.

In Addis Ababa, on the sidelines of an African Union summit, U.S. Secretary of State John Kerry appealed to U.N. Secretary General Ban Ki-moon "to try to get something moving with respect to Syria", according to a pool reporter. Ban told Kerry he and his special Syria envoy Lakhdar Brahimi "are working very hard to convene, to make this Geneva conference a success".

Saudi Arabia, the most powerful Arab adversary of Assad, will want to see the Geneva conference, which could convene in the next few weeks, put the exit of Assad at the top of the agenda, diplomats and coalition members said.

But they said Russia, a longtime ally of Assad, wanted it to focus on a ceasefire although there is scant rapport between opposition politicians abroad and rebels inside Syria.

The inability of the coalition to alter its Islamist-dominated membership and replace a leadership damaged by power struggles is playing into the hands of Assad who, according to Russia, intends to send representatives to the peace conference.

PIVOTAL BATTLE

"The coalition risks undermining itself to the point that its backers may have to look quickly for an alternative with enough credibility on the ground to go to Geneva," a senior opposition source at the talks said.

Senior opposition figures said the coalition was likely to attend the conference, but doubted the meeting would secure their central demand - an immediate deal for Assad to quit.

While the opposition remained riven by differences, the assault by Assad's forces and their Hezbollah allies on Qusair over the past week is evolving into a pivotal battle.

Qusair controls access to Syria's Mediterranean coast, the heartland of Assad's minority Alawite community, and the battle may prove a weighty test of his ability to withstand the revolt.

Hezbollah's intervention is hardening fears that the civil war will cross borders at the volatile heart of the Middle East.

"It is ironic that Lebanon's civil strife is playing itself out in Syria. The opposition remains without coherence and the regime is intent on taking back anything it promises with violence," said one diplomat.

The diplomat was referring to a deepening sectarian divide between Shi'ite and Sunni Muslims in Lebanon, where Syrian troops were present for 29 years, including for most of the Lebanese civil war that ended in 1990.

The death toll in the northern Lebanese city of Tripoli reached 25 on Saturday in the seventh straight day of clashes between Alawite and Sunni factions backing opposing sides in Syria's war, security sources said.

(Additional reporting by Erika Solomon in Beirut and Arshad Mohammed in Addis Ababa; Editing by Pravin Char)

Source: http://news.yahoo.com/syrian-opposition-struggles-unity-battle-rages-012923791.html

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15 Action Stars Who Can Play Our Hero Anytime

With the latest incarnation of the Fast and the Furious franchise -- starring bulked-up actors like Vin Diesel and Paul Walker -- steamrolling into theaters, it feels like a good time to reminisce about some of our favorite action flick hunks.

Source: http://www.ivillage.com/15-hottest-action-stars-movies/1-a-537044?dst=iv%3AiVillage%3A15-hottest-action-stars-movies-537044

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Who the Bluth are you?! Meet the 'Arrested' gang

TV

3 hours ago

The Bluths are back! This Sunday, Orange County?s most dysfunctional TV family returns via Netflix for 15 new episodes of "Arrested Development." It?s been seven long years since fans have heard from this motley crew, so you may need a refresher course on who was hooking up and who had a hook hand.

Here?s a quick guide to where each character?s story line left off.

Source: http://www.today.com/entertainment/who-bluth-are-you-meet-arrested-development-gang-again-6C10057250

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Saturday, May 25, 2013

Obama: Sexual assault threatens trust in military

President Barack Obama congratulates Alexis Marisa Werner with open arms during the United States Naval Academy commencement ceremony in Annapolis, Md., Friday, May 24, 2013. (AP Photo/Patrick Semansky)

President Barack Obama congratulates Alexis Marisa Werner with open arms during the United States Naval Academy commencement ceremony in Annapolis, Md., Friday, May 24, 2013. (AP Photo/Patrick Semansky)

Members of the 2013 graduating class of the United States Naval Academy throw their caps into the air marking the end of their commencement ceremony in Annapolis, Md,. Friday, May 24, 2013, where President Barack Obama spoke. (AP Photo/Pablo Martinez Monsivais)

A graduating U.S. Naval Academy Midshipman marches into the Academy's graduation and commissioning ceremonies, Friday, May 24, 2013, in Annapolis, Md. President Barack Obama urged new graduates to exhibit honor and courage in tackling incidents of sexual assault as they assume leadership positions in the military. (AP Photo/Patrick Semansky)

President Barack Obama congratulates a graduate as another one celebrates at the United States Naval Academy graduation ceremony in Annapolis, Md., Friday, May 24, 2013. (AP Photo/Pablo Martinez Monsivais)

President Barack Obama speaks at the commencement ceremony for the United States Naval Academy in Annapolis, Md., Friday, May 24, 2013. The president urged new graduates to exhibit honor and courage in tackling incidents of sexual assault as they assume leadership positions in the military. (AP Photo/Pablo Martinez Monsivais)

(AP) ? With a growing sexual assault epidemic staining the military, President Barack Obama urged U.S. Naval Academy graduates Friday to remember their honor depends on what they do when nobody is looking and said the crime has "no place in the greatest military on earth."

The commander in chief congratulated the 1,047 midshipmen graduating at the Navy-Marine Corps Memorial Stadium, telling the 841 men and 206 women that they have proven themselves morally by meeting rigorous standards at the academy. But their commencement celebration came in the midst of reports of widespread sexual assault throughout the military, and Obama ended his 20-minute address by recognizing "how the misconduct of some can have effects that ripple far and wide."

"Those who commit sexual assault are not only committing a crime, they threaten the trust and discipline that makes our military strong," Obama said. "That's why we have to be determined to stop these crimes, because they've got no place in the greatest military on Earth."

His pointed comments were aimed at rooting out the problem at a time when Republicans have been criticizing Obama for not responding forcefully enough to controversies including last year's deadly attack in Libya and political targeting at the IRS. But Obama was quick to express outrage over the reports of sexual assault, saying he has no tolerance for it. He summoned military leaders to the White House last week and instructed them to lead a process to root out the problem.

The Pentagon released a report earlier this month estimating that as many as 26,000 military members may have been sexually assaulted last year and that thousands of victims are unwilling to come forward despite new oversight and assistance programs. That figure is an increase over the 19,000 estimated assaults in 2011.

Several recent arrests have added to the military's embarrassment. A soldier at the U.S. Military Academy at West Point was charged with secretly photographing women, including in a bathroom. The Air Force officer who led the service's Sexual Assault Prevention and Response unit was arrested on charges of groping a woman. And the manager of the Army's sexual assault response program at Fort Campbell, Ky., was relieved of his post after his arrest in a domestic dispute with his ex-wife.

The applause that had accompanied earlier portions of Obama's Naval Academy speech, as he mentioned the Navy Seal's killing of Osama bin Laden and called for the building of a powerful 300-ship fleet, fell to silence as he turned to the sexual assault scandal. Midshipmen and spectators watching under cool gray skies as a light rain fell listened silently as he repeated the refrain: "We need your honor."

Obama urged the graduates to use the leadership skills and values learned at the academy to help prevent behavior in the battlefield that can damage the image of the U.S. overseas.

"We need your honor, that inner compass that guides you, not when the path is easy and obvious, but it's hard and uncertain, that tells you the difference between that which is right and that which is wrong," Obama said. "Perhaps it will be the moment when you think nobody's watching. But never forget that honor, like character, is what you do when nobody's looking."

After the midshipmen took their oath of office as Navy ensigns and Marine second lieutenants, the president emerged from the covered stage into the rain to shake the hand of each graduate collecting a diploma. "Folks in the Navy don't mind a little water," the president joked in his speech. The rain stopped just before the whooping graduates threw their caps in the air to end the ceremony.

Obama's address was the second to a military audience in as many days, coming a day after he laid out his counterterrorism vision at the National Defense University where he defended his controversial drone strikes program and renewed his push to close the Guantanamo Bay, Cuba, detention facility.

It's a tradition for presidents to rotate speeches at the commissioning ceremonies of the four service academies. The Naval Academy, about 30 miles from the White House in Annapolis, Md., says 16 presidents have addressed graduates, and Obama is the sixth to do so twice. He also addressed 2009 graduates.

The ceremony and its pageantry could not escape Washington's budget fights. The Navy's Blue Angels aerobatic team won't perform because of budget cuts due to a fight between Obama and congressional Republicans.

But the ceremony also featured a fitting achievement: For the first time in the academy's history, an entire family will have graduated from the school.

Matt Disher was joining his brother Brett and sister Alison, twins who graduated in 2010, as well as his father Tim and mother Sharon as alumni.

"Tim and I never expected anything like this," said Sharon, who graduated in 1980 in the first class that included women. "In fact, if anything we probably discouraged the kids from going, because if you don't come in for the right reason, which is to serve your country, you're not going to last."

Sharon Disher, of Annapolis, wrote the book "First Class: Women Join the Ranks at the Naval Academy" about the difficulties of being in the class of 1980, the first that included women. She said she's disappointed the military is still grappling with sexual assault issues but applauded the president for raising the subject.

"The more we talk about it, the more we're going to do something about it, and that's the thing we never did," she said. "I guess we've just got to keep the conversation going until we fix the problem."

___

Associated Press writer Brian Witte contributed

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-05-24-US-Obama/id-51053793ad774cafbb5d61dba9e3b547

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Obama orders review of guidelines for probing journalists

By Jeff Mason

WASHINGTON (Reuters) - President Barack Obama said on Thursday he directed Attorney General Eric Holder to conduct a review of Department of Justice guidelines for investigations that involve journalists and report back by early July.

Obama has come under criticism for his administration's pursuit of journalists who have reported leaked material.

In recent weeks, it emerged that the Justice Department seized Associated Press phone records as part of a probe into leaks about a 2012 Yemen-based plot to bomb a U.S. airliner and that Fox News correspondent James Rosen had been named a "co-conspirator" in a federal leaks probe involving his reporting on North Korea.

"I'm troubled by the possibility that leak investigations may chill the investigative journalism that holds government accountable," Obama said on Thursday during a foreign policy speech about his administration's counterterrorism objectives.

"Journalists should not be at legal risk for doing their jobs. Our focus must be on those who break the law," Obama said.

Obama said Holder would convene a group of media groups and collect their concerns as part of his review.

Obama said last week he made "no apologies" for his concern about leaks to the media that could compromise U.S. national security or put American military and intelligence officers at risk.

The Department of Justice said in a statement that Holder would report back to the president by July 12 and would meet with experts inside and outside government in addition to media representatives.

"This review is consistent with Attorney General Holder's long-standing belief that freedom of the press is essential to our democracy," the department said in a statement.

"At the same time, the Attorney General believes that leaks of classified information damage our national security and must be investigated using appropriate law enforcement tools."

(Editing by Peter Cooney)

Source: http://news.yahoo.com/obama-orders-review-guidelines-probing-journalists-222939170.html

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Friday, May 24, 2013

German business confidence unexpectedly rebounds

BERLIN (AP) ? German business confidence rebounded this month in an unexpectedly strong showing that sends a hopeful signal for more robust growth in Europe's biggest economy, a closely watched survey found Friday.

The Ifo think tank's confidence index rose to 105.7 points for May from 104.4 last month. The upturn followed two consecutive declines and beat economists' expectations of a very slight increase to 104.5.

The German economy returned to modest growth of just 0.1 percent in the first quarter, just enough to avoid a recession after shrinking in the last three months of 2012.

That performance was weighed down by an exceptionally long winter and the country's central bank said this week that it expects an improvement in the current quarter. Recent industrial orders data also have been promising.

Ifo said this month's improvement in its survey was fueled by companies' brighter view of their current situation, while their outlook for the next six months remained unchanged.

Export expectations have weakened somewhat among companies in the key manufacturing sector, but "continued stimulus from abroad is expected," Ifo said in a statement.

A separate survey showed a significant rise in German consumer confidence as people's expectations for the economy and for their own income improved.

The GfK institute said its forward-looking consumer climate index rose to 6.5 points for June from 6.2 in May, the highest since September 2007, though it cautioned consumer confidence would be vulnerable if Europe's debt crisis escalates again.

With German unemployment low and employees in some sectors recently winning significant pay rises, domestic demand is helping keep the economy on track even as other countries in Europe struggle.

Germany's Federal Statistical Office pointed to household spending, which rose 0.8 percent in the first quarter, as a key driver in the country's return to growth. Detailing the first-quarter performance on Friday, it said exports barely contributed to growth, while investment decreased.

Carsten Brzeski, an economist at ING in Brussels, said "the fog is clearing" over the direction of the German economy, and that a combination of private consumption and a catch-up in industrial activity, particularly in construction, "could deliver decent growth in the second quarter."

However, he cautioned that "the big unknown in the equation remains the export sector," pointing to softer growth in China and economic stagnation in neighboring France.

The Ifo survey is based on monthly responses from some 7,000 companies.

Source: http://news.yahoo.com/german-business-confidence-unexpectedly-rebounds-083015991.html

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Scotland-England split? Some Scots say take the pound, leave the crown

Scotland will vote in 2014 whether to split off from England and the rest of the United Kingdom. Scottish nationalists argue that Scotland would be better off alone.

By William James,?Reuters / May 23, 2013

Scots wave the national flag Thursday, Sept. 11, 1997 on the 700th anniversary of William Wallace's victory over the English at the Battle of Stirling Bridge in 1297. In 2014, Scots will get to vote on whether or not Scotland should remain part of the United Kingdom.

Chris Bacon / AP

Enlarge

Ending Britain's 306-year rule would allow Scotland to reverse generations of economic mismanagement and free its lawmakers to boost economic growth, say Scottish nationalists campaigning to split from the UK.

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'; } else if (google_ads.length > 1) { ad_unit += ''; } } document.getElementById("ad_unit").innerHTML += ad_unit; google_adnum += google_ads.length; return; } var google_adnum = 0; google_ad_client = "pub-6743622525202572"; google_ad_output = 'js'; google_max_num_ads = '1'; google_feedback = "on"; google_ad_type = "text"; // google_adtest = "on"; google_image_size = '230x105'; google_skip = '0'; // --> The Difference between the United Kingdom, Great Britain, the British Isles, and England, and how Scotland and Ireland fit in (or don't).

Independence would not only bring the long-standing and sometimes-troubled union to an end, but allow tax cuts and investment focused on boosting exports to spur growth on the Scottish side of the border.

In an attempt to sour support for independence ahead of a Scottish referendum in September 2014, Britain's rulers have issued a flurry of warnings in recent months about the dangers of Scotland scrapping its union with England.

Scotland, according to the British government, would have trouble keeping the pound; its economy would be dangerously exposed to the vicissitudes of the oil market and its banking sector would be vulnerable to a Cyprus-style debt crisis.

But the Scottish government hit back at those gloomy views with a report entitled "Scotland's Economy: The Case for Independence" which said years of shoddy London policies had cost Scotland 19,000 new jobs and hampered growth for decades.

"The UK government's economic policies have been holding Scotland back for generations," said Scotland's Deputy First Minister Nicola Sturgeon. "Only with the powers of independence can Scotland meet its full potential."

Scotland's $190 billion economy -- roughly the size of New Zealand's -- makes up about 8 percent of the United Kingdom's $2.4 trillion economy, according to most international measures and Scotland's own economic forecasts.

Opinion polls show about a third of Scottish voters want independence, while nearly 60 percent want to stay part of Britain.

KEEP THE POUND

Scotland said that if granted independence it wanted to keep using the British pound under a currency union arrangement and strengthen ties with the European Union, steps which it said could increase exports by 50 percent over four years.

"A currency union would provide the full flexibility to vary tax and spending decisions to target key opportunities and challenges in Scotland," the report said.

It cited tourism, food and drink and manufacturing as some of the industries that would benefit from independence and the freedom to deal directly with partners in Europe and beyond.

Opponents of independence in London have warned Scotland it would have to renegotiate European Union membership as a separate sovereign state and that its share of North Sea oil revenues would also be the subject of discussion.

Alistair Darling, a Scottish politician who served as finance minister under the Labour government between 2007 and 2010, said the economic case for an independent Scotland was "totally unconvincing".

He said oil, gas and renewable energy sectors were dependent on large UK subsidies and that Scotland's financial sector relied heavily upon access to the rest of the British market.

The remaining oil and gas reserves of the North Sea could be worth up to $2.28 trillion according to Scottish government analysis, and the report backs creating a Norwegian-style oil wealth fund to cushion the blow of any future economic shocks.

"Nothing lasts for ever but we know that oil and gas resources are going to last a long time," said Alex Salmond, Scotland's first minister and leader of the Scottish National Party.

An independent Scotland could attract investment by cutting corporation tax, simplifying regulatory structures and providing incentives for companies to invest in training their workers.

A three percent cut in corporation tax could boost economic output by 1.4 percent and raise employment by 1.1 percent by attracting investment over the next 20 years, the report said.

Scotland could also save money with a trimmed down regulation system compared to that of the UK, that created greater certainty for industries and higher levels of protection for consumers, the report said.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/UvHq2pr6GS0/Scotland-England-split-Some-Scots-say-take-the-pound-leave-the-crown

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Vaccine blackjack: IL-21 critical to fight against viral infections

May 23, 2013 ? Scientists at Emory Vaccine Center have shown that an immune regulatory molecule called IL-21 is needed for long-lasting antibody responses in mice against viral infections.

The results are published in the Journal of Virology.

"Our findings highlight how IL-21 could be important in the development of antiviral vaccines," says research associate Ata Ur Rasheed Mohammed, PhD, the first author of the paper. The senior author is Rafi Ahmed, PhD, director of the Emory Vaccine Center and a Georgia Research Alliance Eminent Scholar.

The findings could lead scientists designing future vaccines to incorporate IL-21 directly or to use the ability to stimulate IL-21 as a gauge of vaccine activity. IL-21 was discovered in 2000. Its effects have also been studied in the area of immune responses against HIV, and it has been in clinical trials for skin cancer and kidney cancer and auto-immune disorders.

A main objective of vaccination is to make the recipient's immune system develop antibodies that can neutralize infecting viruses. Signals from IL-21 appear to be necessary for generating long-lived plasma cells, which reside in the bone marrow and secrete antibodies.

Rasheed and his colleagues probed mice that were unable to respond to IL-21, because the mice were engineered to lack the gene for the IL-21 receptor. They examined the altered mice in the context of three different types of viral infections: LCMV (lymphocytic choriomeningitis virus), VSV (vesicular stomatitis virus), and influenza.

When infected with each of the three viruses separately, the altered mice did start to produce antibodies, but antibody levels faded out over the course of around two months. The mice "exhibited a profound defect in generating long-lived plasma cells and in sustaining antibody levels over time," the authors write.

Rasheed's team demonstrated that IL-21 is playing a role in germinal centers, structures in the lymph nodes and spleen where cells that produce high-affinity antibodies are selected. In the IL-21 receptor deficient mice, germinal centers form but are not sustained. IL-21 signals are important both for the antibody-producing cells and for T helper cells that support them, the researchers showed.

The research was supported by the National Institutes of Allergy and Infectious Diseases (P01 AI097092-01A1 and RO1 A1030048) and the Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (UM1AI100663).

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/fI5vU_LEIYU/130523162252.htm

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Sony Privilege introduces Xperia Privilege app

Sony Mobile Communications has brought the Xperia Privilege app to the Netherlands. The app enables Xperia Z users to discover content from Sony and complement their smartphone with accessories and applications. As an introduction, Sony Mobile will give all Xperia Z users EUR 25 worth of credit in May and June for the Music Unlimited or PS store, paid applications and discounts on Sony accessories.

Source: http://feedproxy.google.com/~r/TelecompaperMobileWireless/~3/PQi-q4BVIf0/sony-privilege-introduces-xperia-privilege-app--945322

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Thursday, May 23, 2013

Twitter for Mac updated again, now supports Notification Center

Twitter for Mac has received its second update in a matter of weeks, and this time we're treated to Notification Center support. It's been a long time in coming, especially considering the number of competing apps that already have the same support, but it's better late than never. This comes just a few weeks after the app was updated to support the Retina Display MacBook Pro.

In addition to the Notification Center support, Twitter has thrown in a bunch of fixes, the most notable of which is the fix for Growl notifications not working for users in Lion and Mountain Lion. Grab a copy right now from the Mac App Store, and be sure to tell us if this latest update finally makes you happier with the official Twitter client, or if you're still happier using something else?

    


Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/2jSlXkNN0AM/story01.htm

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Oklahoma tornado was stronger than Hiroshima bomb: How?

When the conditions are exactly right ??and they were, for the tornado that devastated Oklahoma City yesterday ??a tornado can unleash more power than the nuclear bomb dropped on Hiroshima.

By Seth Borenstein,?Associated Press / May 21, 2013

Left, a neighborhood in Moore, Okla., left in ruins on May 4, 1999, after a tornado flattened many houses and buildings in central Oklahoma. Right, flattened houses in Moore on May 20, 2013. Monday's powerful tornado in suburban Oklahoma City loosely followed the path of a killer twister that slammed the region in May 1999.

AP Photo

Enlarge

Everything had to come together just perfectly to create the killer?tornado?in Moore, Okla.: wind speed, moisture in the air, temperature and timing. And when they did, the awesome energy released over that city dwarfed the power of the atomic bomb that leveled Hiroshima.

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On Tuesday, the National Weather Service gave it the top-of-the-scale rating of EF5 for wind speed and breadth, and severity of damage. Wind speeds were estimated at between 200 and 210 mph. The death count is 24 so far, including at least nine children. The United States averages about one EF5 a year, but this was the first in nearly two years.

To get such an uncommon storm to form is "a bit of a Goldilocks problem," said Pennsylvania State University meteorology professor Paul Markowski. "Everything has to be just right."

For example, there must be humidity for a?tornado?to form, but too much can cut the storm off. The same goes with the cold air in a downdraft: Too much can be a storm-killer.

But when the ideal conditions do occur, watch out. The power of nature beats out anything man can create.

"Everything was ready for explosive development yesterday," said Colorado State University meteorology professor Russ Schumacher, who was in Oklahoma launching airborne devices that measured the energy, moisture and wind speeds on Monday. "It all just unleashed on that one area."

Several meteorologists contacted by The Associated Press used real time measurements, some made by Schumacher, to calculate the energy released during the storm's 40-minute life span. Their estimates ranged from 8 times to more than 600 times the power of the Hiroshima bomb, with more experts at the high end. Their calculations were based on energy measured in the air and then multiplied over the size and duration of the storm.

An EF5?tornado?has the most violent winds on Earth, more powerful than a hurricane. The strongest winds ever measured were the 302 mph reading, measured by radar, during the EF5?tornado?that struck Moore on May 3, 1999, according to Jeff Masters, meteorology director at the Weather Underground.

Still, when it comes to weather events, scientists usually know more about and can better predict hurricanes, winter storms, heat waves and other big events.

Source: http://rss.csmonitor.com/~r/feeds/science/~3/0MhY9mG-8rw/Oklahoma-tornado-was-stronger-than-Hiroshima-bomb-How

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